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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TP73
All Species:
10.3
Human Site:
Y309
Identified Species:
25.19
UniProt:
O15350
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15350
NP_001119712.1
636
69623
Y309
R
K
A
D
E
D
H
Y
R
E
Q
Q
A
L
N
Chimpanzee
Pan troglodytes
XP_001160425
586
65734
R299
Q
M
T
S
I
K
K
R
R
S
P
D
D
E
L
Rhesus Macaque
Macaca mulatta
P56424
393
43637
L111
H
G
S
Y
G
F
R
L
G
F
L
H
S
G
T
Dog
Lupus familis
XP_546740
1086
116755
Y755
R
K
A
D
E
D
H
Y
R
E
Q
Q
A
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJP2
631
69077
Y301
R
K
A
D
E
D
H
Y
R
E
Q
Q
A
L
N
Rat
Rattus norvegicus
Q9JJP6
680
76742
I359
R
K
A
D
E
D
S
I
R
K
Q
Q
V
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512581
688
77295
I368
R
K
A
D
E
D
S
I
R
K
Q
Q
V
S
D
Chicken
Gallus gallus
P10360
367
40151
T85
P
S
P
V
V
P
S
T
E
D
Y
G
G
D
F
Frog
Xenopus laevis
P07193
363
40674
Y81
T
D
D
Y
A
G
K
Y
G
L
Q
L
D
F
Q
Zebra Danio
Brachydanio rerio
P79734
373
41881
T91
S
G
T
A
K
S
V
T
C
T
Y
S
P
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
54.8
29.8
53.9
N.A.
89.4
53.8
N.A.
53.4
29.5
29
29.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
69.3
40.8
56.6
N.A.
93.5
68.8
N.A.
67.7
40.7
40.8
41.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
0
93.3
N.A.
100
60
N.A.
60
0
13.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
13.3
100
N.A.
100
73.3
N.A.
73.3
6.6
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
50
10
10
0
0
0
0
0
0
0
30
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
0
10
10
50
0
50
0
0
0
10
0
10
20
20
20
% D
% Glu:
0
0
0
0
50
0
0
0
10
30
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
10
0
0
0
10
10
% F
% Gly:
0
20
0
0
10
10
0
0
20
0
0
10
10
10
0
% G
% His:
10
0
0
0
0
0
30
0
0
0
0
10
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
20
0
0
0
0
0
0
0
% I
% Lys:
0
50
0
0
10
10
20
0
0
20
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
10
0
10
10
10
0
30
20
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
20
% N
% Pro:
10
0
10
0
0
10
0
0
0
0
10
0
10
0
0
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
60
50
0
0
10
% Q
% Arg:
50
0
0
0
0
0
10
10
60
0
0
0
0
0
0
% R
% Ser:
10
10
10
10
0
10
30
0
0
10
0
10
10
20
10
% S
% Thr:
10
0
20
0
0
0
0
20
0
10
0
0
0
0
10
% T
% Val:
0
0
0
10
10
0
10
0
0
0
0
0
20
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
20
0
0
0
40
0
0
20
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _